Publikationen
M. A. S. Al-Shaibani , T. Sakoleva , L. A. Živković , H. P. Austin , M. Dörr , L. Hilfert , E. Haak , U. T. Bornscheuer , T. Vidaković-Koch , “ Product Distribution of Steady–State and Pulsed Electrochemical Regeneration of 1,4-NADH and Integration with Enzymatic Reaction .” , ChemistryOpen 2024 , 13 , e202400064. https://doi.org/10.1002/open.202400064
M. A. S. Al-Shaibani , S. Verma , L. A. Zivkovic , and T. Vidakovic-Koch , “ Revisiting the Reaction Mechanism of Electrochemical 1,4-NADH Regeneration on Carbon Electrodes .” ChemCatChem ( 2025 ): e00975. https://doi.org/10.1002/cctc.202500975
Schoenmakers P, Rad R, Ihl A, Weickardt I, Guillouet S, Apfel UP, Lauterbach L. 2025 Isopropanol production from carbon dioxide by Cupriavidus necator using a zero-gap cell with culture broth as catholyte. iScience. doi: 10.1016/j.isci.2025.113018.
Barone, G.D., Somvilla, I., Meier, H.P.F. et al. Industrial applicability of enzymatic and whole-cell processes for the utilization of C1 building blocks. Nat Commun 16, 7066 (2025). https://doi.org/10.1038/s41467-025-60777-3
Y. Peng, T. Sakoleva, N. Rockstroh, S. Bartling, P. Schoenmakers, G. Lim, D. Wei, T. Bayer, M. Dörr, D. Böttcher, L. Lauterbach, H. Junge, U. T. Bornscheuer, M. Beller, ChemSusChem 2025, 18, e202401811. https://doi.org/10.1002/cssc.202401811
A. Maier, L. M. Mguni, A. C. R. Ngo, D. Tischler, ChemCatChem 2024, 16, e202401021. https://doi.org/10.1002/cctc.202401021
Schwarz I, Rieck A, Mehmood A, Bublitz R, Bongers L, Weuster-Botz D, Fellinger TP (2024) PEM electrolysis in a stirred-tank bioreactor enables autotrophic growth of Clostridium ragsdalei with CO2 and electrons. ChemElectroChem 2024, 11, e202300344. https://doi.org/10.1002/celc.202300344
Gemünde A, Rossini E, Lenz O, Frielingsdorf S, Holtmann D (2024). Chemoorganotrophic electrofermentation by Cupriavidus necator using redox mediators. Bioelectrochemistry, 158, 108694. https://doi.org/10.1016/j.bioelechem.2024.108694
Abt M, Franzreb M, Jestädt M, Tschöpe A (2023) Three-phase fluidized bed electrochemical reactor for the scalable generation of hydrogen peroxide at enzyme compatible conditions. Chemical Engineering Journal. https://doi.org/10.1016/j.cej.2023.146465
Siedentop R, Prenzel T, Waldvogel SR, Rosenthal K, Lütz S (2023) Reaction Engineering and Comparison of Electroenzymatic and Enzymatic ATP Regeneration Systems. ChemElectroChem: e202300332. https://doi.org/10.1002/celc.202300332
Sayoga G, Abt M, Teetz N, Bueschler V, Liese A, Franzreb M, Holtmann D (2023) Quantitative and non-quantitative assessments of enzymatic electrosynthesis: a case study of parameter requirements. ChemElectroChem: e202300226. https://doi.org/10.1002/celc.202300226
Gemünde A, Gail J, Janek J, Holtmann D (2023) e-Cuvettes parallelize electrochemical and photometric measurements in cuvettes and facilitate applications in bio-electrochemistry. Biosensors and Bioelectronics: X, 100378. https://doi.org/10.1016/j.biosx.2023.100378
Stöckl M, Gemünde A, Holtmann D (2023) Microbial electrotechnology – Intensification of bioprocesses through the combination of electrochemistry and biotechnology. Physical Sciences Reviews. https://doi.org/10.1515/psr-2022-0108
Sayoga GV, Bueschler VS, Beisch H, Holtmann D, Zeng A, Fiedler B, Ohde D, Liese A (2023) Application of the all-in-one electrode for in situ H2O2 generation in hydroxylation catalyzed by unspecific peroxygenase from Agrocybe aegerita. Molecular Catalysis, 547, 113325. https://doi.org/10.1016/j.mcat.2023.113325
Rohbohm N, Sun T, Blasco-Gómez R, Byrne JM, Kapplerdf A, Angenent LT (2023) Carbon oxidation with sacrificial anodes to inhibit O2 evolution in membrane-less bioelectrochemical systems for microbial electrosynthesis. EES Catalysis. https://doi.org/10.1039/D3EY00141E
Kruth S, Nett M (2023) Aurachins, Bacterial Antibiotics Interfering with Electron Transport Processes. Antibiotics, 12(6):1067. https://doi.org/10.3390/antibiotics12061067
Boto ST, Bardl B, Harnisch F, Rosenbaum MA (2023) Microbial electrosynthesis with Clostridium ljungdahlii benefits from hydrogen electron mediation and permits a greater variety of products. GreenChem. https://doi.org/10.1039/D3GC00471F
Gemünde A, Gail J, Holtmann D (2023) Anodic Respiration of Vibrio natriegens in a Bioelectrochemical System. ChemSusChem. https://doi.org/10.1002/cssc.202300181
Gizewski J, vd Sande L, Holtmann D (2023) Contribution of electrobiotechnology to sustainable development goals. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2023.02.009
Sakoleva T, Austin HP, Tzima C, Dörr M, Bornscheuer UT (2023) Discovery and Characterization of a Baeyer-Villiger Monooxygenase Using Sequence Similarity Network Analysis. ChemBioChem, 24. https://doi.org/10.1002/cbic.202200746
Siedentop R, Siska M, Möller N, Lanzrath H, von Lieres E, Lütz S, Rosenthal K (2023) Bayesian Optimization for an ATP-Regenerating In Vitro Enzyme Cascade. Catalysts, 23;13(3):468. https://doi.org/10.3390/catal13030468
Koleda O, Prenzel T, Winter J, Hirohata T, de Jesús Gálvez-Vázquez M, Schollmeyer D, Inagi S, Suna E, Waldvogel SR (2023) Simple and scalable electrosynthesis of 1H-1-hydroxy-quinazolin-4-ones. Chemical Science, 14(10):2669-75. https://doi.org/10.1039/D3SC00266G
Siedentop R, Dziennus M, Lütz S, Rosenthal K (2023) Debottlenecking of an In Vitro Enzyme Cascade Using a Combined Model- and Experiment-Based Approach. Chemie Ingenieur Technik. https://doi.org/10.1002/cite.202200170
Kruth S, Zimmermann CJ-M, Kuhr K, Hiller W, Lütz S, Pietruszka J, Kaiser M, Nett M (2023) Generation of Aurachin Derivatives by Whole-Cell Biotransformation and Evaluation of Their Antiprotozoal Properties. Molecules, 28(3):1066. https://doi.org/10.3390/molecules28031066
Lai B, Krömer J, Aulenta F, Wu H, Nikel PI (2023) Exploiting synergies between microbial electrochemical technologies and synthetic biology. Microb Biotechnol, 16: 485-488. https://doi.org/10.1111/1751-7915.14208
Winter J, Prenzel T, Wirtanen T, Schollmeyer D, Waldvogel SR (2022) Direct Electrochemical Synthesis of 2,3‐Disubstituted Quinoline N‐oxides by Cathodic Reduction of Nitro Arenes. Chemistry–A European Journal, 29(12):e202203319. https://doi.org/10.1002/chem.202203319
Kruth S, Schibajew L, Nett M (2022) Biocatalytic production of the antibiotic aurachin D in Escherichia coli. AMB Expr, 12, 138. https://doi.org/10.1186/s13568-022-01478-8
Becker JM, Lielpetere A, Szczesny J, Bichon S, Gounel S, Mano N, Schuhmann W (2022) Wiring of bilirubin oxidases with redox polymers on gas diffusion electrodes for increased stability of self-powered biofuel cells-based glucose sensing. Bioelectrochemistry, 149. https://doi.org/10.1016/j.bioelechem.2022.108314
Dolan SK, Wijaya A, Kohlstedt M, Gläser L, Brear P, Silva-Rocha R, Wittmann C, Welch M (2022) Systems-wide dissection of organic acid assimilation in Pseudomonas aeruginosa Reveals a Novel Path to Underground Metabolism. Mbio 13, 6(2022). https://doi.org/10.1128/mbio.02541-22
Becker JM, Lielpetere A, Szczesny J, Junqueira JRC, Rodriguez-Macia P, Birell JA, Conzuelo F, Schuhmann W (2022) Bioelectrocatalytic CO2 Reduction by Redox Polymer-Wired Carbon Monoxide Dehydrogenase Gas Diffusion Electrodes. ACS Appl. Mater. Interfaces, 14, 46421−46426. https://doi.org/10.1021/acsami.2c09547
Abdollahi M, Al Sbei S, Rosenbaum MA, Harnisch F (2022) The oxygen dilemma: The challenge of the anode reaction for microbial electrosynthesis from CO2. Frontiers in Microbiology, 13. https://doi.org/10.3389/fmicb.2022.947550
Häuser L, Erben J, Pillot G, Kerzenmacher S, Dreher W, Küstermann E (2022) In vivo characterization of electroactive biofilms inside porous electrodes with MR Imaging. RSC Adv., 12, 17784-17793. https://doi.org/10.1039/D2RA01162J
Zhao F, Brix AC, Lielpetere A, Schuhmann W, Conzuelo F (2022) On the mediated electron transfer of immobilized galactose oxidase for biotechnological applications. Chemistry–A European Journal. 2022 May 25;28(30):e202200868. https://doi.org/10.1002/chem.202200868
Gemünde A, Lai B, Pause L, Krömer J, Holtmann D (2022) Redox Mediators in Microbial Electrochemical Systems. ChemElectroChem, 9. https://doi.org/10.1002/celc.202200216
Kohlstedt M, Weimer A, Weiland F, Stolzenberger J, Selzer M, Sanz M, Kramps L, Wittmann C (2022) Biobased PET from lignin using an engineered cis, cis-muconate-producing Pseudomonas putida strain with superior robustness, energy and redox properties. Metabolic engineering, 72, 337–352. https://doi.org/10.1016/j.ymben.2022.05.001
Kinner A, Nerke P, Siedentop R, Steinmetz T, Classen T, Rosenthal K, Nett M, Pietruszka J, Lütz S (2022) Recent Advances in Biocatalysis for Drug Synthesis. Biomedicines, 10(5):964. https://doi.org/10.3390/biomedicines10050964
Siedetop R, Rosenthal K (2022) Industrially Relevant Enzyme Cascades for Drug Synthesis and Their Ecological Assessment. International Journal of Molecular Sciences, 23(7):3605. https://doi.org/10.3390/ijms23073605
Becker JM, Lielpetere A, Szczesny J, Ruff A, Conzuelo F, Schuhmann W (2022) Assembling a Low-volume Biofuel Cell on a Screen-printed Electrode for Glucose Sensing. Electroanalysis, 34: 1629–1637. https://doi.org/10.1002/elan.202200084
Stockinger P, Borlinghaus N, Sharma M, Aberle B, Grogan G, Pleiss J, Nestl BM (2021) Inverting the stereoselectivity of an NADH-dependent imine-reductase variant. ChemCatChem, 13, 5210. https://doi.org/10.1002/cctc.202101057
Siedentop R, Claaßen C, Rother D, Lütz S, Rosenthal K (2021) Getting the Most Out of Enzyme Cascades: Strategies to Optimize In Vitro Multi-Enzymatic Reactions. Catalysts, 11(10):1183. https://doi.org/10.3390/catal11101183
Wirtanen T, Prenzel T, Tessonnier JP, Waldvogel SR (2021) Cathodic corrosion of metal electrodes—how to prevent it in electroorganic synthesis. Chemical Reviews, 6;121(17):10241-70. https://doi.org/10.1021/acs.chemrev.1c00148